Fructus Perillae Frutescensis

Tóm tắt

Tía tô (Quả) (Fructus Perillae frutescensis) là quả của cây Tía tô (Perilla frutescens), thuộc họ Bạc hà (Lamiaceae). Tía tô là loài bản địa phổ biến ở các khu vực Đông Á, Nam Á, và Đông Nam Á, đồng thời được di thực sang châu Âu, châu Mỹ, và châu Phi. Theo kinh nghiệm sử dụng trong y học cổ truyền, quả Tía tô có công năng phát tán phong hàn, lý khí khoan hung, giải uất, hóa đờm, an thai, và giải độc do cua cá. Tác dụng dược lý chính bao gồm kháng khuẩn, giảm viêm, hỗ trợ tiêu hóa, hóa đờm, và làm dịu triệu chứng do nhiễm lạnh. Thành phần hóa học của quả Tía tô bao gồm các hoạt chất như perilla-andehyt (C10H14O), limonen, α-pinen, dihydrocumin (C10H14O), xyanin clorit (C27H31O16Cl), adenin (C5H5N5), và acginin (C6H14N4O2), mang lại hiệu quả trong điều trị các bệnh lý liên quan đến phong hàn, khí uất, và đờm.

I. Thông tin về dược liệu

Định danh

• Dược liệu tiếng Việt: Tía Tô - Quả
• Dược liệu tiếng Trung: nan (nan)
• Dược liệu tiếng Anh: nan
• Dược liệu latin thông dụng: Fructus Perillae Frutescensis
• Dược liệu latin kiểu DĐVN: nan
• Dược liệu latin kiểu DĐVN: nan
• Dược liệu latin kiểu thông tư: nan
• Bộ phận dùng: Quả (Fructus)

Mô tả dược liệu

Theo dược điển Việt nam V: nan

Mô tả dược liệu theo thông tư chế biến dược liệu theo phương pháp cổ truyền: nan

Chế biến

Chế biến theo dược điển việt nam V: nan

Chế biến theo thông tư: nan

II. Thông tin về thực vật

Dược liệu Tía Tô - Quả từ bộ phận Quả từ loài Perilla frutescens.

Mô tả thực vật: Tía tô là một loại cỏ mọc hằng năm, cao chừng 0,5-1,5cm. Thần thẳng đứng có lông. Lá mọc đổi, hình trứng, đầu nhọn, mép có răng cưa to; phiến lá dài 4-12cm rộng 2,50-10cm, màu tím hoặc xanh tím, trên có lông màu tím. Người ta phân biệt thứ tía tô có lá màu tím hung là Perilla ocymoides var. purpurascens và thứ tía tô có lá màu lục, chỉ có gân màu hung (Perilla ocymoides var.bicolor). Cuống lá ngắn 2-3cm. Hoa nhỏ, màu trắng hoặc tím nhạt, mọc thành từng chùm ở kẽ lá hay đầu cành, chùm dài 6-20cm. Quả là hạch nhỏ, hình cầu, đường kính 1mm, màu nâu nhạt, có mạng.

Tài liệu tham khảo: “Những cây thuốc và vị thuốc Việt Nam” - Đỗ Tất Lợi Trong dược điển Việt nam, loài Perilla frutescens được sử dụng làm dược liệu.

Phân loại thực vật của Perilla frutescens

Kingdom: Plantae

Phylum: Tracheophyta

Order: Lamiales

Family: Lamiaceae

Genus: Perilla

Species: Perilla frutescens

Phân bố trên thế giới: United States of America, Chinese Taipei, China, New Zealand, Netherlands

Phân bố tại Việt nam: Không có ghi nhận ở Việt Nam

III. Thành phần hóa học

Theo tài liệu của GS. Đỗ Tất Lợi: (1) perilla- andehyt C10H14O, limonen, α- pinen, dihydrocumin C10H14O, xyanin clorit C27H31O16Cl, adenin C5H5N5 và acginin C6H14N4O2. (2)

Theo cơ sở dữ liệu lotus, loài Perilla frutescens đã phân lập và xác định được 283 hoạt chất thuộc về các nhóm Tetrapyrroles and derivatives, Cinnamic acids and derivatives, Diazines, Epoxides, Organooxygen compounds, Benzene and substituted derivatives, Glycerolipids, Coumarins and derivatives, Prenol lipids, Benzoxepines, Oxanes, Steroids and steroid derivatives, Naphthalenes, Organic oxides, Fatty Acyls, Benzodioxoles, Cyclobutane lignans, Tetrahydrofurans, Flavonoids, Phenol ethers, Heteroaromatic compounds, Saturated hydrocarbons, Oxepanes, Phenols, Unsaturated hydrocarbons trong bảng dưới đây.

chemicalTaxonomyClassyfireClass	smiles_count
Benzene and substituted derivatives	97
Benzodioxoles	48
Benzoxepines	111
Cinnamic acids and derivatives	1028
Coumarins and derivatives	22
Cyclobutane lignans	237
Diazines	61
Epoxides	32
Fatty Acyls	614
Flavonoids	2825
Glycerolipids	61
Heteroaromatic compounds	16
Naphthalenes	14
Organic oxides	21
Organooxygen compounds	1119
Oxanes	26
Oxepanes	25
Phenol ethers	64
Phenols	213
Prenol lipids	4770
Saturated hydrocarbons	6
Steroids and steroid derivatives	934
Tetrahydrofurans	23
Tetrapyrroles and derivatives	263
Unsaturated hydrocarbons	20

Danh sách chi tiết các hoạt chất như sau:

Nhóm Benzene and substituted derivatives.

Nhóm Benzodioxoles.

Nhóm Benzoxepines.

Nhóm Cinnamic acids and derivatives.

Nhóm Coumarins and derivatives.

Nhóm Cyclobutane lignans.

Nhóm Diazines.

Nhóm Epoxides.

Nhóm Fatty Acyls.

Nhóm Flavonoids.

Nhóm Glycerolipids.

Nhóm Heteroaromatic compounds.

Nhóm Naphthalenes.

Nhóm Organic oxides.

Nhóm Organooxygen compounds.

Nhóm Oxanes.

Nhóm Oxepanes.

Nhóm Phenol ethers.

Nhóm Phenols.

Nhóm Prenol lipids.

Nhóm Saturated hydrocarbons.

Nhóm Steroids and steroid derivatives.

Nhóm Tetrahydrofurans.

Nhóm Tetrapyrroles and derivatives.

Nhóm Unsaturated hydrocarbons.

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IV. Tác dụng dược lý

Theo tài liệu quốc tế: nan

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V. Dược điển Việt Nam V

Soi bột

nan

Vi phẫu

nan

Định tính

nan

Định lượng

nan

Thông tin khác

• Độ ẩm: nan
• Bảo quản: nan

VI. Dược điển Hồng kong

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VII. Y dược học cổ truyền

nan

Tên vị thuốc: nan

Tính: nan

Vị: nan

Quy kinh: nan

Công năng chủ trị: nan

Phân loại theo thông tư: nan

Tác dụng theo y dược cổ truyền: nan

Chú ý: nan

Kiêng kỵ: nan

Cấu trúc hóa học của các hoạt chất thuộc nhóm Benzene and substituted derivatives là isovanillic acid (LTS0247446), benzaldehyde (LTS0094193), 1-butyl 2-(2-methylpropyl) phthalate (LTS0006259), methyl salicylate (LTS0128373), methyl 3,4-dihydroxybenzoate (LTS0057841).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Benzodioxoles là dillapiol (LTS0226542), myristicin (LTS0180101).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Benzoxepines là 2-{8-methoxy-3,12-dioxatricyclo[7.5.0.0²,⁶]tetradeca-1,4,6,8,10,13-hexaen-4-yl}propan-2-ol (LTS0068640), 2-[(4r)-8-methoxy-3,12-dioxatricyclo[7.5.0.0²,⁶]tetradeca-1(9),2(6),7,10,13-pentaen-4-yl]propan-2-ol (LTS0091247), 2-{8-methoxy-3,12-dioxatricyclo[7.5.0.0²,⁶]tetradeca-1(9),2(6),7,10,13-pentaen-4-yl}propan-2-ol (LTS0047209).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Cinnamic acids and derivatives là (s)-rosmarinic acid (LTS0124509), 3-(3,4-dihydroxyphenyl)-2-{[3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid (LTS0128557), (2s)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0217338), rosemary acid (LTS0207820), 3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0047172), 3,4-dihydroxycinnamic acid (LTS0128050), methyl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0080306), 3-(3,4-dihydroxyphenyl)-3-{[3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid (LTS0181102), (1r)-1-(3,4-dihydroxyphenyl)-3-methoxy-3-oxopropyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0115339), [4-(prop-1-en-2-yl)cyclohexyl]methyl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0094486), 1-(3,4-dihydroxyphenyl)-3-methoxy-3-oxopropyl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0199479), (2r)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0244535), 2-(3,5-dihydroxyphenyl)ethenyl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0172102), ethenyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0192219), ethenyl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0149344), methyl caffeate (LTS0163009), (3r)-3-(3,4-dihydroxyphenyl)-3-{[(2e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid (LTS0117569), 1-(3,4-dihydroxyphenyl)-3-ethoxy-3-oxopropyl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0214025), (1r)-1-(3,4-dihydroxyphenyl)-3-ethoxy-3-oxopropyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0226277), caffeic acid (LTS0027481), (1z)-2-(3,5-dihydroxyphenyl)ethenyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0005376), [(1r,4r)-4-(prop-1-en-2-yl)cyclohexyl]methyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0012143), 2-(3,4-dihydroxyphenyl)ethenyl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0038661), (1z)-2-(3,4-dihydroxyphenyl)ethenyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0043560).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Coumarins and derivatives là esculetin (LTS0067593).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Cyclobutane lignans là 1-[(3r,4r)-2,3-dimethyl-4-(2,4,5-trimethoxyphenyl)cyclobutyl]-2,4,5-trimethoxybenzene (LTS0077205), 1-[(1r,2s,3s,4r)-2,3-dimethyl-4-(2,4,5-trimethoxyphenyl)cyclobutyl]-2,4,5-trimethoxybenzene (LTS0032112), magnosalin (LTS0100649), 1-[2,3-dimethyl-4-(2,4,5-trimethoxyphenyl)cyclobutyl]-2,4,5-trimethoxybenzene (LTS0165645).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Diazines là pyrazine, 2-methyl-3-propyl- (LTS0061073), 2-ethylpyrazine (LTS0030974), pyrazine, 2-butyl-3-methyl- (LTS0167507), 2-ethyl-3-methylpyrazine (LTS0156574), 2-isobutyl-3-methyl pyrazine (LTS0094695).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Epoxides là (3z,7e)-1,5,5,8-tetramethyl-12-oxabicyclo[9.1.0]dodeca-3,7-diene (LTS0107049).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Fatty Acyls là 3-octanol (LTS0055953), cis-3-hexenol (LTS0132156), myristic acid (LTS0102566), 1-octen-3-ol (LTS0057101), trans-2-hexenol (LTS0046040), [3-oxo-2-(5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}pent-2-en-1-yl)cyclopentyl]acetic acid (LTS0075323), 5-phenyl-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}pentanoic acid (LTS0024981), [(1r,2r,3r)-2-[(2z)-pent-2-en-1-yl]-3-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}cyclopentyl]acetic acid (LTS0184640), (2s,3r,4s,5s,6r)-2-{[(3s)-3,7-dimethylocta-1,6-dien-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol (LTS0102692), [2-(pent-2-en-1-yl)-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}cyclopentyl]acetic acid (LTS0187703), α-linolenic acid (LTS0275508), tuberonic acid glucoside (LTS0123953), α linolenic acid (LTS0132789), 2-[(3,7-dimethylocta-1,6-dien-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol (LTS0054728), linoleic (LTS0013198), (3r)-5-phenyl-3-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}pentanoic acid (LTS0017300), 3-hexenol (LTS0009177).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Flavonoids là apigenin 7-o-β-glucoside (LTS0252743), 5-{[(2s,3r,4s,5s,6r)-6-{[(2-carboxyacetyl)oxy]methyl}-3,4,5-trihydroxyoxan-2-yl]oxy}-2-(3,4-dihydroxyphenyl)-7-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[3-(4-hydroxyphenyl)prop-2-enoyl]oxy}methyl)oxan-2-yl]oxy}-1λ⁴-chromen-1-ylium (LTS0274063), luteolin 7-o-glucoside (LTS0227450), luteolin (LTS0017052), chrysoeriol (LTS0095766), [(2r,3s,4s,5r,6s)-3,4,5-trihydroxy-6-{[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy}oxan-2-yl]methyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0181993), 7-{[(2s,3r,4r,5s,6r)-3,4-dihydroxy-6-(hydroxymethyl)-5-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-2-(3,4-dihydroxyphenyl)-5-hydroxychromen-4-one (LTS0134088), (3,4,5-trihydroxy-6-{[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy}oxan-2-yl)methyl 3-(3,4-dihydroxyphenyl)prop-2-enoate (LTS0234047), apigetrin (LTS0157591), 7-{[3,4-dihydroxy-6-(hydroxymethyl)-5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-2-(3,4-dihydroxyphenyl)-5-hydroxychromen-4-one (LTS0185283), 7-{[3,4-dihydroxy-6-(hydroxymethyl)-5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one (LTS0096625), chamomile (LTS0104946), (2s,3s,4s,5r,6s)-5-{[(2r,3r,4s,5s,6s)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3,4-dihydroxy-6-{[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy}oxane-2-carboxylic acid (LTS0195961), 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one (LTS0158292), 7-{[(2s,3r,4r,5s,6r)-3,4-dihydroxy-6-(hydroxymethyl)-5-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one (LTS0273662), 6-[(6-carboxy-4,5-dihydroxy-2-{[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy}oxan-3-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid (LTS0008851), 2-(3,4-dihydroxyphenyl)-7-hydroxy-5-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[3-(4-hydroxyphenyl)prop-2-enoyl]oxy}methyl)oxan-2-yl]oxy}-1λ⁴-chromen-1-ylium (LTS0003904), 6-{[5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid (LTS0192632), 6-[(6-carboxy-2-{[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy}-4,5-dihydroxyoxan-3-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid (LTS0148966), luteolin 7-o-glucuronide (LTS0081420), (2s)-7-{[(2s,3r,3as,6r,6ar)-3-{[(2s,3r,3ar,6r,6ar)-3,6-dihydroxy-5-oxo-tetrahydro-2h-furo[3,2-b]furan-2-yl]oxy}-6-hydroxy-5-oxo-tetrahydro-2h-furo[3,2-b]furan-2-yl]oxy}-2-(3,4-dihydroxyphenyl)-5-hydroxy-2,3-dihydro-1-benzopyran-4-one (LTS0177917), methyl (2s,3s,4s,5r,6s)-6-{[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylate (LTS0161447), 7-{[3-({3,6-dihydroxy-5-oxo-tetrahydro-2h-furo[3,2-b]furan-2-yl}oxy)-6-hydroxy-5-oxo-tetrahydro-2h-furo[3,2-b]furan-2-yl]oxy}-2-(3,4-dihydroxyphenyl)-5-hydroxy-2,3-dihydro-1-benzopyran-4-one (LTS0200764), cyanin betaine (LTS0259506), 7-hydroxy-2-(4-hydroxy-3-oxidophenyl)-5-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[3-(4-hydroxyphenyl)prop-2-enoyl]oxy}methyl)oxan-2-yl]oxy}-1λ⁴-chromen-1-ylium (LTS0104152), carthamidin (LTS0150711), methyl 6-{[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylate (LTS0088544), cyanin (LTS0264308), 6-{[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid (LTS0175049), (2s,3s,4s,5r,6s)-5-{[(2r,3r,4s,5s,6s)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-6-{[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy}-3,4-dihydroxyoxane-2-carboxylic acid (LTS0203367), (2r)-5,6,7-trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzopyran-4-one (LTS0112515), scutellarin (LTS0121337), 2-(3,4-dihydroxyphenyl)-6,7-dihydroxychromen-4-one (LTS0040385).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Glycerolipids là oleoyl glycerol (LTS0013965), glyceryl palmitate (LTS0073260).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Heteroaromatic compounds là perillene (LTS0083458).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Naphthalenes là naphthalene (LTS0254484).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Organic oxides là β-cyclocitral (LTS0195727).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Organooxygen compounds là egomaketone (LTS0225736), 3-hydroxytyrosol 3-o-glucoside (LTS0092215), (2e)-1-(furan-3-yl)-4-methylpent-2-en-1-one (LTS0182663), perilla ketone (LTS0184428), 1-penten-3-one (LTS0122674), 1-octen-3-one (LTS0098886), cis-3-hexenal (LTS0200949), cis-2-pentenol (LTS0214162), 1-penten-3-ol (LTS0174520), 2-furyl pentyl ketone (LTS0063505), 1-(furan-3-yl)-4-methylpent-2-en-1-one (LTS0051939), 3-pentanone (LTS0030661), prunasin (LTS0130138), (2r,3s,4s,5r,6s)-2-(hydroxymethyl)-6-[2-methoxy-5-(prop-2-en-1-yl)phenoxy]oxane-3,4,5-triol (LTS0165847), (2r)-2-{[(2r,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-2-phenylacetonitrile (LTS0169902), 3,4-dihydroxybenzaldehyde (LTS0251601), 2-(hydroxymethyl)-6-{[5-methoxy-6-(prop-2-en-1-yl)-2h-1,3-benzodioxol-4-yl]oxy}oxane-3,4,5-triol (LTS0226061), 2-phenyl-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}acetonitrile (LTS0258953), (2r)-2-phenyl-2-{[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}acetonitrile (LTS0274248), benzyl glucopyranoside (LTS0210495), 2-(hydroxymethyl)-6-[2-methoxy-5-(prop-2-en-1-yl)phenoxy]oxane-3,4,5-triol (LTS0210812), methyl α-galactoside (LTS0026855), 3-hexenal (LTS0027368), benzyl β-d-glucoside (LTS0184698), 2-(hydroxymethyl)-6-[2-methoxy-4-(prop-2-en-1-yl)phenoxy]oxane-3,4,5-triol (LTS0047093), 3-methyl-1-(3-methylfuran-2-yl)but-2-en-1-one (LTS0203687), 2-hexanol (LTS0106528), 3-methyl-1-(3-methylfuran-2-yl)butan-1-one (LTS0065675), methyl-α-d-mannoside (LTS0012148), 2-{[4,5-dihydroxy-6-(hydroxymethyl)-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-2-phenylacetonitrile (LTS0023638), eugenyl glucoside (LTS0095502), (s)-prunasin (LTS0035643), (2r,3s,4s,5r,6s)-2-(hydroxymethyl)-6-{[5-methoxy-6-(prop-2-en-1-yl)-2h-1,3-benzodioxol-4-yl]oxy}oxane-3,4,5-triol (LTS0109210), 3-octanone (LTS0272728).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Oxanes là 1,8-cineole (LTS0166505).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Oxepanes là limonene-1,2-epoxide (LTS0225957).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Phenol ethers là elemicin (LTS0188875), β-asarone (LTS0003070), tarragon (LTS0245226).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Phenols là 2-methoxy-5-(prop-1-en-1-yl)phenol (LTS0170720), 2-methoxy-3-(prop-1-en-1-yl)phenol (LTS0274885), eugenol (LTS0052342), 5-[(3,4-dihydroxyphenyl)methyl]-4-hydroxy-5h-1,3-oxazol-2-one (LTS0194169), (2r)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanimidic acid (LTS0126859), 2-methoxy-4-propenylphenol (LTS0086128), (5s)-5-[(3,4-dihydroxyphenyl)methyl]-4-hydroxy-5h-1,3-oxazol-2-one (LTS0030862), 3-(3,4-dihydroxyphenyl)-2-hydroxypropanimidic acid (LTS0010885), isoeugenol (LTS0136836).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Prenol lipids là ursolic acid (LTS0250838), pomolic acid (LTS0196537), perillaldehyde, (LTS0028488), tormentic acid (LTS0102591), farnesene (LTS0057150), (4as,6as,6br,8as,10s,12ar,12bs,14br)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid (LTS0087204), epi-maslinic acid (LTS0044982), (1s,2r,4as,6as,6br,8ar,10s,11r,12ar,12br,14bs)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydro-1h-picene-4a-carboxylic acid (LTS0234764), corosolic acid (LTS0231285), (4as,6as,6br,8ar,10r,11s,12ar,12br,14bs)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid (LTS0066479), methyl geranate (LTS0181597), carvone, (+)- (LTS0027671), 1,10-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid (LTS0147544), linalool, (+-)- (LTS0128839), [(1r,4r)-4-(prop-1-en-2-yl)cyclohexyl]methanol (LTS0231168), terpineol (LTS0136148), α pinene (LTS0132416), 4-isopropyl-1,6-dimethyl-2,3,4,4a,7,8-hexahydronaphthalene (LTS0270743), 10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydro-1h-picene-4a-carboxylic acid (LTS0166564), β-farnesene (LTS0067925), delta-cadinene (LTS0019321), oleanolic acid (LTS0117717), (-)-germacrene d (LTS0059194), (5r)-1-methyl-5-(prop-1-en-2-yl)cyclohex-1-ene (LTS0056347), carotenoid (LTS0205297), β-terpinene (LTS0106377), piperitenone (LTS0074451), (r)-β-bisabolene (LTS0077209), caryophyllene oxide (LTS0159789), trans-β-ocimene (LTS0049765), 1-methyl-3-(prop-1-en-2-yl)cyclohex-1-ene (LTS0114229), nerolidol (LTS0197738), humulene (LTS0263171), (3r,6e)-nerolidol (LTS0145065), limonene, (LTS0155981), β-caryophyllen (LTS0141501), neocembrene (LTS0173151), caryophyllene (LTS0085212), thujene (LTS0268450), piperitone (LTS0273145), (1z,6z,8s)-8-isopropyl-1-methyl-5-methylidenecyclodeca-1,6-diene (LTS0065195), β-caryophyllene oxide (LTS0213960), 1-ethenyl-1-methyl-2-(prop-1-en-2-yl)-4-(propan-2-ylidene)cyclohexane (LTS0082746), 4-[(1e,3z,5z,7e,9e,11e,13z,15z,17e)-18-(4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]-3,5,5-trimethylcyclohex-3-en-1-ol (LTS0249716), (-)-β-bisabolene (LTS0009940), carvacrol (LTS0012882), perillylalcohol (LTS0009128), α-carotene (LTS0224243), carvone (LTS0196605), (+)-α-carotene (LTS0200789), violaxanthin (LTS0102265), 1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid (LTS0013744), (-)-perillyl alcohol (LTS0083880), α-humulene (LTS0076944), β-bourbonene (LTS0074484), (-)-limonene (LTS0205325), 1,1,7-trimethyl-4-methylidene-octahydro-1ah-cyclopropa[e]azulene (LTS0063570), cuparene (LTS0028747), α-myrcene (LTS0115731), (e,z)-farnesol (LTS0182151), β-bourbonene (LTS0167513), terpinolene (LTS0104525), (+)-pulegone (LTS0094277), β-pinene (LTS0117550), cymene (LTS0181568), 3-hydroxy-4-(prop-1-en-2-yl)cyclohex-1-ene-1-carbaldehyde (LTS0186815), (2e,4e,6e)-3,7,11-trimethyldodeca-2,4,6,10-tetraene (LTS0251704), 1-methylidene-4-(prop-1-en-2-yl)cyclohexane (LTS0196110), (4s)-4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxylic acid (LTS0134732), 3,7-dimethyl-2,6-octadienal (LTS0141353), 10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid (LTS0167090), 3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl 4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxylate (LTS0140700), camphene (LTS0267242), (6e)-2,6-dimethyl-10-methylidenedodeca-2,6-diene (LTS0154516), 10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydro-1h-picene-4a-carboxylic acid (LTS0122037), β-elemene (LTS0225699), (3s,4r)-3-hydroxy-4-(prop-1-en-2-yl)cyclohex-1-ene-1-carbaldehyde (LTS0087048), phellandrene (LTS0157173), thujopsene (LTS0181981), α-bergamotene (LTS0226115), 1-methyl-4-(1,2,2-trimethylcyclopentyl)benzene (LTS0261288), (4e,8e)-4,8,11,11-tetramethylcycloundeca-1,4,8-triene (LTS0118116), crocetin (LTS0129423), (-)-α-curcumene (LTS0216936), nerolidol (LTS0262980), (2z,4e,6e)-3,7,11-trimethyldodeca-2,4,6,10-tetraene (LTS0198484), α-limonene (LTS0244943), (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-{[(4s)-4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methoxy}oxane-3,4,5-triol (LTS0268551), antheraxanthin (LTS0210072), α-copaene (LTS0207598), (+)-perillaldehyde (LTS0052244), sabinene (LTS0224133), 2-(hydroxymethyl)-6-{[4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methoxy}oxane-3,4,5-triol (LTS0043500), (1as,4as,7as,7br)-1,1,7-trimethyl-4-methylidene-octahydro-1ah-cyclopropa[e]azulene (LTS0160636), neoxanthin (LTS0227522), oleanolic acid (LTS0141130), ionone (LTS0252546), geraniol (LTS0258838), β-ocimene (LTS0242381), α-terpinyl acetate (LTS0172943), (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-{[(1r,4r)-4-(prop-1-en-2-yl)cyclohexyl]methoxy}oxane-3,4,5-triol (LTS0183828), curcumene (LTS0190074), (1r,2s,7s,8s)-8-isopropyl-1,3-dimethyltricyclo[4.4.0.0²,⁷]dec-3-ene (LTS0190031), farnesol (LTS0059667), perillic acid (LTS0043386), caryophyllene (LTS0131870), neoxanthin (LTS0000701), (-)-thujopsene (LTS0021824), 2-(hydroxymethyl)-6-{[4-(prop-1-en-2-yl)cyclohexyl]methoxy}oxane-3,4,5-triol (LTS0028579), (2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (4s)-4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxylate (LTS0075972), (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-{[(1s,4s)-4-(prop-1-en-2-yl)cyclohexyl]methoxy}oxane-3,4,5-triol (LTS0245159), humula-1(11),4,8-triene (LTS0029053), α-citral (LTS0246122), (-)-perillaldehyde (LTS0025470), geranyl diphosphate (LTS0051684).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Saturated hydrocarbons là hexane (LTS0209095).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Steroids and steroid derivatives là (3as,5ar,5bs,7as,10r,11r,11as,13as,13bs)-11-hydroxy-1-(hydroxymethyl)-3,3,5a,5b,10,11,13b-heptamethyl-3ah,4h,5h,6h,7h,8h,9h,10h,11ah,13h,13ah-cyclopenta[a]chrysene-7a-carboxylic acid (LTS0003486), stigmast-5-en-3-ol, (3β)- (LTS0204616), sitosterol (LTS0168132), sitogluside (LTS0201798), 2-{[1-(5-ethyl-6-methylheptan-2-yl)-9a,11a-dimethyl-1h,2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol (LTS0158828), castasterone (LTS0111493), estrone (LTS0023699), campesterol (LTS0029429), phytosterol (LTS0029311), stigmasterol (LTS0024262), 11-hydroxy-1-(hydroxymethyl)-3,3,5a,5b,10,11,13b-heptamethyl-3ah,4h,5h,6h,7h,8h,9h,10h,11ah,13h,13ah-cyclopenta[a]chrysene-7a-carboxylic acid (LTS0045760), campesterol (LTS0046755).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Tetrahydrofurans là linalyl oxide (LTS0065533).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Tetrapyrroles and derivatives là methyl (21s,22s)-16-ethenyl-11-ethyl-12,17,21,26-tetramethyl-4-oxo-22-(3-oxo-3-{[(2e)-3,7,11,15-tetramethylhexadec-2-en-1-yl]oxy}propyl)-7,23,24,25-tetraazahexacyclo[18.2.1.1⁵,⁸.1¹⁰,¹³.1¹⁵,¹⁸.0²,⁶]hexacosa-1(23),2(6),5(26),7,9,11,13,15,17,19-decaene-3-carboxylate (LTS0002371), methyl (21s,22s)-16-ethenyl-11-ethyl-12-(hydroxymethylidene)-17,21,26-trimethyl-4-oxo-22-(3-oxo-3-{[(2e)-3,7,11,15-tetramethylhexadec-2-en-1-yl]oxy}propyl)-7,23,24,25-tetraazahexacyclo[18.2.1.1⁵,⁸.1¹⁰,¹³.1¹⁵,¹⁸.0²,⁶]hexacosa-1,5(26),6,8,10,13(25),14,16,18,20(23)-decaene-3-carboxylate (LTS0059915).

Cấu trúc hóa học của các hoạt chất thuộc nhóm Unsaturated hydrocarbons là (3e,5e)-3,7-dimethylocta-1,3,5-triene (LTS0270900).